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Re: Recreational Drugs - Should they be legal ?

Posted: Mon Nov 29, 2010 1:36 am
by lone dragon
OK you wish solid information, not joke sites

[spoiler]To conclude, this meta-analysis quantitatively reviewed
published studies to determine the relationship between
ecstasy use and memory function within four categories;
verbal short term memory, verbal working memory, visuospatial
short term memory, and visuospatial working
memory. Across the studies, ecstasy users showed significantly
reduced memory function in all four memory
domains. Lifetime ecstasy consumption significantly predicted
the effect size associated with working memory
whereby greater consumption of ecstasy was predictive of
greater impairment in working memory performance relative
to controls. Short-term memory and working memory were
differentially related to the extent of ecstasy use over the
lifetime, which could reflect a difference in the reversibility
of cognitive changes in each type of memory due to ecstasy
use, or the action of alternative mediating variables.[/spoiler]

this is this years so very current and Review
Differential Effects of Ecstasy on Short-Term and Working Memory: A Meta-Analysis

[spoiler]Conclusions Our findings suggest that even a first low cumulative dose of Ecstasy is associated with decline in verbal memory. Although the performance of the group of incident Ecstasy users is still within the normal range and the immediate clinical relevance of the observed deficits is limited, long-term negative consequences cannot be excluded.[/spoiler]

Another meta analysis

Archives of Psychiatry.
Vol. 64 No. 6, June 2007.

Do you want more?

This a valid and cogent studies in which are at the forefront of scientific facts.

Re: Recreational Drugs - Should they be legal ?

Posted: Mon Nov 29, 2010 1:55 am
by Iƒrit
and most of those media hypes probably were not on MDMA, but another form of methylendioxyamphetamine. When doing my own research i have never found any infomation stating clearly it causing holes in your brain, not to say it may not, but you'd think in the near 100 years its been around there would be more information indicating brain decay....

Re: Recreational Drugs - Should they be legal ?

Posted: Mon Nov 29, 2010 5:39 am
by MEZZANINE
Iƒrit wrote:and most of those media hypes probably were not on MDMA, but another form of methylendioxyamphetamine. When doing my own research i have never found any infomation stating clearly it causing holes in your brain, not to say it may not, but you'd think in the near 100 years its been around there would be more information indicating brain decay....


Exactly, and the problem of purity and knowing what you are taking is proper MDMA is something that legalising would solve.

Also the media funding comes from advertising, they dont want to bite the hand that feeds them.

Government funding comes from taxation, in the UK the taxation on cigarettes and aclohol are greater than the entire NHS funding, basically smokers and drinkers pay for UK heathcare, and tax on petrol/diesel/road tax is several times higher than all road and public transport spending. The government dont want people dropping an E costing £5 in a night, they want people to keep going back to the bar and spend £60-70+ on drinks instead.



@ Lonedragon, my quotes had links, they were all respectable trustworthy sources like the BBC, one of the UKs top Police officers, and the UKs top drug expert, not sure what your sources are but google can find stuff to support any argument if you look hard enough. If you really believe MDMA is more harmful that cigarettes & alcohol I think you're looking in the wrong places.

Re: Recreational Drugs - Should they be legal ?

Posted: Mon Nov 29, 2010 1:02 pm
by lone dragon
MEZZANINE wrote:
Iƒrit wrote:and most of those media hypes probably were not on MDMA, but another form of methylendioxyamphetamine. When doing my own research i have never found any infomation stating clearly it causing holes in your brain, not to say it may not, but you'd think in the near 100 years its been around there would be more information indicating brain decay....


Exactly, and the problem of purity and knowing what you are taking is proper MDMA is something that legalising would solve.

Also the media funding comes from advertising, they dont want to bite the hand that feeds them.

Government funding comes from taxation, in the UK the taxation on cigarettes and aclohol are greater than the entire NHS funding, basically smokers and drinkers pay for UK heathcare, and tax on petrol/diesel/road tax is several times higher than all road and public transport spending. The government dont want people dropping an E costing £5 in a night, they want people to keep going back to the bar and spend £60-70+ on drinks instead.



@ Lonedragon, my quotes had links, they were all respectable trustworthy sources like the BBC, one of the UKs top Police officers, and the UKs top drug expert, not sure what your sources are but google can find stuff to support any argument if you look hard enough. If you really believe MDMA is more harmful that cigarettes & alcohol I think you're looking in the wrong places.

I dont doubt your sites but fact one of those sources is this years current forefront research if you knew about research you would know what a meta-analysis is. If you wont listen to current evidence then what do you want! Oh and I dont see any neuroscience data in your argument.

Re: Recreational Drugs - Should they be legal ?

Posted: Mon Nov 29, 2010 7:51 pm
by Thriller
lone dragon wrote:OK you wish solid information, not joke sites

[spoiler]To conclude, this meta-analysis quantitatively reviewed
published studies to determine the relationship between
ecstasy use and memory function within four categories;
verbal short term memory, verbal working memory, visuospatial
short term memory, and visuospatial working
memory. Across the studies, ecstasy users showed significantly
reduced memory function in all four memory
domains. Lifetime ecstasy consumption significantly predicted
the effect size associated with working memory
whereby greater consumption of ecstasy was predictive of
greater impairment in working memory performance relative
to controls. Short-term memory and working memory were
differentially related to the extent of ecstasy use over the
lifetime, which could reflect a difference in the reversibility
of cognitive changes in each type of memory due to ecstasy
use, or the action of alternative mediating variables.[/spoiler]

this is this years so very current and Review
Differential Effects of Ecstasy on Short-Term and Working Memory: A Meta-Analysis

[spoiler]Conclusions Our findings suggest that even a first low cumulative dose of Ecstasy is associated with decline in verbal memory. Although the performance of the group of incident Ecstasy users is still within the normal range and the immediate clinical relevance of the observed deficits is limited, long-term negative consequences cannot be excluded.[/spoiler]

Another meta analysis

Archives of Psychiatry.
Vol. 64 No. 6, June 2007.

Do you want more?

This a valid and cogent studies in which are at the forefront of scientific facts.


I would like a link to the orginal study

Keith R. Laws, Joy Kokkalis
Article first published online: 10 JUL 2007

DOI: 10.1002/hup.857

which was done in 2007

not "this years"; but fairly current

Meta analysis is very tricky, since when comparing different studies against each other; the number of variables to control for increases dramatically.

I would like to read the work for myself.

Re: Recreational Drugs - Should they be legal ?

Posted: Mon Nov 29, 2010 10:21 pm
by lone dragon
Thriller wrote:
lone dragon wrote:OK you wish solid information, not joke sites

[spoiler]To conclude, this meta-analysis quantitatively reviewed
published studies to determine the relationship between
ecstasy use and memory function within four categories;
verbal short term memory, verbal working memory, visuospatial
short term memory, and visuospatial working
memory. Across the studies, ecstasy users showed significantly
reduced memory function in all four memory
domains. Lifetime ecstasy consumption significantly predicted
the effect size associated with working memory
whereby greater consumption of ecstasy was predictive of
greater impairment in working memory performance relative
to controls. Short-term memory and working memory were
differentially related to the extent of ecstasy use over the
lifetime, which could reflect a difference in the reversibility
of cognitive changes in each type of memory due to ecstasy
use, or the action of alternative mediating variables.[/spoiler]

this is this years so very current and Review
Differential Effects of Ecstasy on Short-Term and Working Memory: A Meta-Analysis

[spoiler]Conclusions Our findings suggest that even a first low cumulative dose of Ecstasy is associated with decline in verbal memory. Although the performance of the group of incident Ecstasy users is still within the normal range and the immediate clinical relevance of the observed deficits is limited, long-term negative consequences cannot be excluded.[/spoiler]

Another meta analysis

Archives of Psychiatry.
Vol. 64 No. 6, June 2007.

Do you want more?

This a valid and cogent studies in which are at the forefront of scientific facts.


I would like a link to the orginal study

Keith R. Laws, Joy Kokkalis
Article first published online: 10 JUL 2007

DOI: 10.1002/hup.857

which was done in 2007

not "this years"; but fairly current

Meta analysis is very tricky, since when comparing different studies against each other; the number of variables to control for increases dramatically.

I would like to read the work for myself.

the first one was done in 2010
http://www.springerlink.com/content/hp55706675247038/

2007

http://www.psy.herts.ac.uk/pub/klaws/HUP857.pdf